Cerimon Pharmaceuticals, Inc., announced it hold initiate a Phase I clinical enquiry of a new-fangled diclofenac sodium patch, the Company’s forefront discomfort desirable quality. The study will authority sanctuary, tolerability, and systemic pharmacokinetics of a topical patch formulation of diclofenac sodium, a non-steroidal anti-inflammatory linctus (NSAID), inwardly 16 unprocessed volunteers. The Phase I study be looked-for to be completed in the fourth quarter of 2007. Following the final result of this study, Cerimon procedure to fast initiate late-stage efficacy and safety study of its diclofenac sodium patch in patients next to acute musculoskeletal pain.
“Topical diclofenac is the second counteractive article of job Cerimon has advanced into clinical studies this year, succeeding the launching of Phase IIb carrying out test all for Simulect(R) (basiliximab) in the hasty quarter,” stated Paul Sekhri, President and CEO of Cerimon Pharmaceuticals. “We be self-aggrandizing of this progress and judge the diclofenac patch will address the bazaar have need of for protected and potent topical pain therapy.
Currently, topical NSAIDs are market in Europe, Japan, and other parts of the world, but not in the U.S. Their control in treat musculoskeletal pain is the facility to deliver drug head-on to the put by the side of vastness with minimal systemic bringing to hurricane lantern. Given the systemic line-up effects of perfectionist non-topical NSAIDs, by okay as the bill of somewhat a few COX-2 inhibitors, we believe emerging a investigational managing picking is an major aspiration for the medical expand.” Pain Market Musculoskeletal pain is pain that affect the muscles, ligaments, and tendons. Acute musculoskeletal lesion are widespread and can go down during sports undertakings, training, or other unqualified activities. They habitually initiation suffering in the red to soft tissue injuries, such as sprains, strain, and ropey contusions. While in the main not sober, these injuries are often irritated and result in stopgap disability. Acute musculoskeletal injuries largely demand swift treatment. Primary treatment with fresh tighten is often support via regime of anti-inflammatory drugs. Optimal topical treatment should consent to gallop acute pain and cut growth in the broken area to right normal removal. In assimilation, it should be safe and trouble-free to administer.
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